Abstract: Oncologic Safety of Fat Grafting in Breast Reconstruction: A New Clinically Relevant Animal Model of Residual Breast Cancer
نویسندگان
چکیده
METHODS: Collagenase derived from Clostridium Histolyticum was used in a randomized, double-blinded, placebo controlled study on a total of 19 healthy subjects, each with two biopsy-proven lipomas of similar size (one to receive drug and one to receive placebo) at two independent investigational centers (Office of Z. Gerut and Dept. of Plastic Surgery Vanderbilt Univ. Med Ctr.). An independent pharmacist prepared the research drug and the placebo for injection and the two indiscernible preparations were randomized for injection into the two lipomas of each subject; all staff including the investigators, as well as the subject were blinded.
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Abstract: Determining the Oncologic Safety of Autologous Fat Grafting as a Reconstructive Modality: an Institutional Review of Breast Cancer Recurrence Rates and Surgical Outcomes
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